Nicotinamide is bad for the skin

In clinical practice, nicotinamide is a derivative of vitamin B3. Although it has the effect of locking water and moisturizing the skin after use, it will also cause certain harm to the skin after use. For example, after application, it can show skin flushing, itching, rash and other manifestations. At the same time, some patients can show high blood sugar, high uric acid, arrhythmia and other manifestations. Even some patients can be accompanied by dizziness, nausea, dyspepsia, upper abdominal discomfort and other manifestations. The reason for these adverse symptoms is that nicotinamide contains some impurities, which often cause skin allergy irritation. Therefore, for these adverse symptoms, it is recommended to perform skin allergy test behind the ear before use.