Is schistosomiasis liver cirrhosis serious?

Schistosome cirrhosis is a very serious disease.

Schistosome cirrhosis is an end-stage liver disease caused by schistosomiasis infection. After schistosomiasis enters the human body, it mainly parasitizes and lays eggs in the mesenteric veins distributed in the portal vein. Most eggs flow to the liver along the blood vessels and form granulomas in the liver. If these granulomas are not removed, fibrous scars and fibrous nodules will form in the liver, eventually leading to cirrhosis.

Patients with cirrhosis may develop serious complications such as liver failure, ascites, massive gastrointestinal bleeding, etc. These complications may endanger the patient's life. In addition, patients may also develop splenomegaly and portal hypertension. These symptoms are related to the inflammatory reaction caused by the long-term existence of schistosomiasis eggs in the body and repeated stimulation of the immune system after infection. This inflammatory reaction can lead to liver tissue damage.