Which cancer is the most painful?

There is no clinical definition of which cancer is most painful in late stages, but pancreatic cancer in late stages is often considered to be very painful.

The pancreas is located deep in the abdomen and has endocrine and exocrine functions. When pancreatic cancer progresses to advanced stages, tumors often invade surrounding tissues and nerves, causing severe pain. This pain can be persistent and unbearable, seriously affecting the patient's quality of life. In addition, there are abundant nerve plexuses around the pancreas, and cancer cells easily invade these nerves, causing neuropathic pain. This pain is often radioactive and can radiate to the back, waist, etc., and conventional pain relief methods may not be effective.

For such patients, a combination of pain relief methods and psychological support is needed to minimize their pain and improve their quality of life.