What are the clinical manifestations of advanced cancer patients before they die

Patients with advanced cancer may experience pain, dyspnea, fatigue, loss of appetite, nausea, vomiting, confusion, coma, and multiple organ failure before death. Patients with advanced cancer may experience the following clinical manifestations before death: 1. Pain: Patients with advanced cancer may experience unbearable pain, especially when the tumor invades the nerves or metastasizes to the bones. Pain may affect sleep, diet, and daily life. 2. Dyspnea: When cancer spreads to the lungs or affects respiratory function, patients may experience symptoms of breathing difficulties. This may be caused by lung fluid accumulation, lung infection, or other respiratory problems. 3. Fatigue and weakness: Patients with advanced cancer often feel extremely tired and weak, which may be caused by the body expending energy to fight cancer and side effects of treatment.4. Loss of appetite and weight loss: Cancer affects appetite, leading to loss of appetite and weight loss. This may lead to malnutrition and debility.5. Nausea and vomiting: Chemotherapy, radiation, or the cancer itself may cause nausea and vomiting, affecting the patient's quality of life.6. Confusion and coma: In some cases, patients with advanced cancer may experience confusion, coma, or other neurological symptoms, which may be caused by brain metastases or other serious comorbidies.7. Dyspnea: When cancer spreads to the lungs or affects respiratory function, patients may experience symptoms of breathing difficulties. This may be caused by fluid accumulation in the lungs, lung infection, or other respiratory problems. 8. Multiple organ failure: In advanced cancer, the patient's body may not be able to maintain the normal function of various organs, resulting in multiple organ failure, which is one of the common causes of death. It is important to note that symptoms may vary from patient to patient and may gradually worsen. If symptoms occur, family members should inform their doctor promptly and provide appropriate supportive care to relieve symptoms and improve quality of life, as recommended by their doctor. Family members should also provide psychological and emotional support to help patients through the difficulties.