What is diffuse large B lymphoma?

Diffuse large B-cell lymphoma is a common non-Hodgkin lymphoma and may recur after treatment. If recurrence occurs, appropriate treatment measures should be taken. Here are some suggestions for how to manage diffuse large B-cell lymphoma recurrence: 1. Reassessment: First, a comprehensive assessment of the patient is required, including symptoms, signs, and imaging (such as CT, PET-CT, etc.) and laboratory tests, etc. to determine the location and extent of recurrence. 2. Treatment plan selection: According to the recurrence situation and the patient's physical condition, the doctor will formulate a personalized treatment plan. Treatment plan may include chemotherapy, radiotherapy, targeted therapy, immunotherapy, etc., or a combination of multiple treatments. Chemotherapy: It is one of the common treatments for diffuse large B-cell lymphoma after recurrence. Commonly used chemotherapy drugs include cyclophosphamide, doxorubicin, vincristine, prednisone, etc. Chemotherapy can control the disease by killing tumor cells. Radiation: For patients with local recurrence or specific site involvement. Radiation can use radiation to kill tumor cells. Targeted therapy: Immunotherapy: Attacks tumor cells by activating the patient's own immune system, such as chimeric antigen receptor T cell immunotherapy (CAR-T cell therapy), etc. 3. Comprehensive treatment: During the treatment process, comprehensive treatment strategies may improve the treatment effect. This may include the application of treatment methods such as surgery and hematopoietic stem cell transplantation. 4. Supportive treatment: At the same time, patients also need to receive supportive treatment to alleviate symptoms and improve quality of life. This may include nutritional support, pain management, anti-infective therapy, etc. Regular follow-up: Regular follow-up, including imaging, laboratory tests, etc., is required after treatment to monitor changes in the condition. The doctor will adjust the treatment plan or conduct further treatment according to the results of the review. It should be noted that the treatment after recurrence of diffuse large B-cell lymphoma needs to be formulated according to individual circumstances. Patients should actively cooperate with the doctor's treatment and follow the doctor's recommendations for treatment and follow-up. In addition, patients and family members can also consult professional nutritionists, psychologists, etc. for comprehensive support and help. Key information: 1. Diffuse large B-cell lymphoma needs comprehensive evaluation after recurrence, and individualized treatment plan should be formulated according to recurrence. 2. Treatment methods include chemotherapy, radiotherapy, targeted therapy, immunotherapy, etc., or combination of multiple methods. 3. Comprehensive treatment and supportive treatment can improve treatment effect and quality of life. 4. Regular review is an important link in monitoring disease condition and adjusting treatment.