Side effects of sorafenib in treatment of liver cancer

Sorafenib is a multi-target oral antitumor drug, mainly used for the treatment of advanced renal cell carcinoma and hepatocellular carcinoma. It can inhibit tumor cell growth and angiogenesis. Common side effects include diarrhea and skin reactions. It is contraindicated in pregnant women and lactating women. During use, it is necessary to check regularly and inform doctors of other drugs being used. Sorafenib is a multi-targeted oral anti-tumor drug used primarily for the treatment of inoperable advanced renal cell carcinoma and inoperable or distant metastatic hepatocellular carcinoma. Efficacy and action: Sorafenib's main efficacy is to exert anti-tumor effects by inhibiting tumor cell growth and angiogenesis. Sorafenib can inhibit Raf kinase activity, thereby blocking intracellular signal transduction pathways, inhibiting tumor cell proliferation and survival. In addition, sorafenib can also inhibit vascular endothelial growth factor receptor (VEGFR) activity, inhibit angiogenesis, thereby cutting off the nutrient supply of tumor cells and promoting tumor cell apoptosis. Contraindications: It is contraindicated in patients with severe allergic reactions to sorafenib or inactive ingredients of the drug. Usage: Sorafenib is usually administered orally and is recommended to be taken 1 hour before or 2 hours after a meal. When taking sorafenib, it should be swallowed whole, not chewed or crushed. Identification tips: Since sorafenib is a prescription drug, it should be used under the guidance of a doctor. When purchasing sorafenib, pay attention to choosing regular channels and carefully check the packaging and labeling of the drug to ensure the quality and safety of the drug. Side effects/contraindications/contraindications: Common side effects of sorafenib include diarrhea, skin reactions, hand-foot syndrome, hypertension, fatigue, loss of appetite, weight loss, etc. During the use of sorafenib, you should pay close attention to changes in your body and inform your doctor if you experience serious discomfort or intolerable side effects. In addition, sorafenib may cause harm to the fetus and should be contraindicated in pregnant and lactating women. Risk warning:

Sorafenib may cause serious side effects, such as bleeding, thrombosis, heart failure, etc. During the use of sorafenib, regular physical examinations, including ECG, blood routine, biochemical tests, etc., should be performed to monitor the side effects and efficacy of the drug. In addition, sorafenib may interact with other drugs, affecting the efficacy of the drug or increasing the risk of side effects.

During the use of sorafenib, the doctor should be informed of other drugs being used so that the doctor can adjust the treatment regimen. In conclusion, sorafenib is an effective antitumor drug, but it should be used with caution for side effects and contraindicated populations, and follow the doctor's advice.