Basic principle of sartan antihypertensive drugs in treating iga nephropathy

Sartan antihypertensive drugs

include losartan, irbesartan, telmisartan, is the latest class of antihypertensive drugs in clinical use, in fact, it can be said that sartan antihypertensive drugs protect the kidney. When it comes to

sartan antihypertensive drugs, angiotensin II is hydrolyzed into angiotensin I, angiotensin I becomes angiotensin II under the action of angiotensin II, which can stimulate the secretion of aldosterone. This system is called renin-angiotensin-aldosterone system.

Under normal circumstances, renin-angiotensin-aldosterone system plays an important role in maintaining blood pressure and ensuring blood supply of heart and brain.