Causes of acute renal failure in nephrotic syndrome

? Patients with nephrotic syndrome are prone to hypovolemia and vascular lesions. Patients are very sensitive to changes in volume and blood pressure. Mild fluid loss, inappropriate diuresis and hypotension may lead to acute renal failure.

Second, patients with nephrotic syndrome are prone to renal interstitial edema, which may also lead to acute renal failure.

Third, severe proteinuria may cause acute renal failure due to tubular blockage due to protein casts.

Fourth, acute renal failure may occur due to contraction of renal arterioles due to increased renin angiotensin activity.