Metformin weight loss?

Metformin has a certain weight loss effect when used in patients with type 2 diabetes. The study showed that in China newly diagnosed type 2 diabetes patients treated with metformin alone for 16 weeks, the weight of normal, overweight and obese patients decreased by 1.47 kg, 2.81 kg and 2.92 kg respectively. The larger the patient's height and body mass index and waist circumference, the more weight loss after metformin treatment. Metformin combined with insulin has been shown to reduce weight gain by 2.28 to 3.85 kg compared with insulin alone. The mechanism of weight loss with metformin is unclear, and metformin is not approved for weight loss in non-diabetic populations.