Why insulin resistance?

Why insulin resistance occurs: The most common cause of insulin resistance is obesity, especially abdominal obesity. Specific reviews include, first, structural abnormalities of insulin, second, abnormalities of insulin cell membrane receptors, and third, genetic mutations. Diseases such as structural abnormalities of insulin, abnormalities of glucose transfer factor 4, or other genetic mutations can also cause insulin resistance. Insulin is like a key, so the receptor of insulin cell membrane is equivalent to its door. As long as the key cannot open the door, it will cause abnormal action of insulin, cause excessive insulin secretion, and finally cause abnormal blood sugar.