What are the causes of type H hypertension?

The main cause of H-type hypertension is elevated homocysteine (Hcy) levels, which can damage vascular endothelial cells and increase the risk of cardiovascular and cerebrovascular diseases. In addition to nutrient deficiency, age, gender, genetic factors, eating habits, smoking, drinking, etc. may also affect Hcy levels. Hcy is a sulfur-containing amino acid that is an intermediate in methionine metabolism. Under normal circumstances, Hcy is metabolized into harmless substances in the body, but when the body lacks nutrients such as folic acid, vitamin B6 and vitamin B12, Hcy levels will increase. Elevated Hcy levels increase the risk of cardiovascular and cerebrovascular diseases because Hcy can damage vascular endothelial cells, promote platelet aggregation, increase blood viscosity, and lead to vascular stenosis and obstruction. In addition, Hcy can oxidize LDL cholesterol to form oxidized LDL cholesterol, further damaging vascular endothelial cells and accelerating the process of atherosclerosis. In addition to nutrient deficiency, age, gender, genetic factors, dietary habits, smoking, alcohol consumption, etc. may also affect Hcy levels. For example, age, male sex, family history of hyperhomocysteinemia, etc. are risk factors for elevated Hcy levels. In addition, high-salt diet, high-protein diet, smoking, alcohol consumption, etc. may also lead to elevated Hcy levels. Therefore, for H-type hypertension patients, in addition to controlling blood pressure, folic acid, vitamin B6 and vitamin B12 and other nutrients are needed to reduce Hcy levels and reduce the risk of cardiovascular and cerebrovascular diseases. At the same time, attention should also be paid to healthy diet, smoking cessation and alcohol restriction to control Hcy levels. In addition, for patients with hypertension, especially older patients with family history of cardiovascular disease, smoking, diabetes and other high-risk factors, Hcy levels should be regularly detected in order to detect and treat H-type hypertension in time.