What does pernicious anaemia mean?

Pernicious anaemia is a condition in which DNA synthesis is impaired, resulting in megaloblastic development.

Megaloblastic development is usually due to DNA synthesis disorders and nuclear arrest, resulting in unbalanced nuclear and cytoplasmic development and the formation of megalocytes larger than normal cells. Pernicious anemia is a nutritional deficiency disease, generally related to genetic, metabolic disorders, insufficient nutrient intake and other factors, which will affect the normal function of multiple systems, causing patients to appear fatigue, dizziness, fatigue, cognitive decline, sensory disorders, ataxia and other symptoms.