Midnight nausea. What's going on?

1, duodenal ulcer

disease is usually related to

gastric acid and pepsin, Helicobacter pylori infection and other reasons, in the middle of the night on an empty stomach, a large amount of gastric acid has not been neutralized by food, can be discharged into the duodenum, and then stimulate the ulcer surface, causing nausea, vomiting and other symptoms.

2, gastroesophageal reflux

gastroesophageal reflux is usually related to anti-reflux structure and function damage, esophageal clearance reduced and other reasons, sleep in the middle of the night, stomach contents can reflux to the esophagus, causing nausea, vomiting and other symptoms.

3, acute cholecystitis

This disease is usually related to cystic duct obstruction, bacterial infection and other reasons, acute cholecystitis often sudden onset at night, patients can feel nausea, abdominal pain and so on.