Is poems syndrome a blood cancer?


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Hematological cancer generally refers to leukemia, POEMS syndrome does not belong to leukemia.
Leukemia is a malignant clonal disease of hematopoietic stem cells, most of which are caused by genetic factors, physical stimulation, chemical stimulation, etc., resulting in uncontrolled proliferation and abnormal differentiation of blood cells. The clinical manifestations of patients are mainly bleeding, skin purpura, high fever, immune abnormalities, etc. POEMS syndrome is a disease related to plasma cell clone proliferation, mainly caused by human herpesvirus type 8 infection and vascular endothelial growth factor stimulation, and its clinical manifestations are peripheral neuropathy, endocrine dysfunction, skin changes, etc. In
summary, the nature, etiology and clinical manifestations of the two diseases are different, so POEMS syndrome does not belong to leukemia.