Pepsinogen I and II are low. What's going on?

Low levels of pepsinogen I and II may be related to unreasonable diet, drug factors, stomach lesions and other factors.

1. Irrational diet

If the diet lacks protein, vitamins and other nutrients, or long-term irregular diet, overeating, etc., it may affect the normal function of gastric mucosa, resulting in decreased secretion of pepsinogen.

2. Drug factors

Some drugs may stimulate the gastric mucosa, resulting in decreased secretion of pepsinogen by gastric mucosa, resulting in low levels of pepsinogen.

3. Gastric lesions Low

levels of pepsinogen I and II may be manifestations of stomach diseases, such as gastritis, gastric ulcer, gastric cancer, etc., which may lead to decreased secretion of pepsinogen by gastric mucosa, resulting in low levels of pepsinogen.