Children hypertension and neuroendocrine related?

Hypertension in children is related to abnormal function of neuroendocrine system. Possible mechanisms include abnormal secretion of RAAS, adrenaline, noradrenaline, insulin and other hormones, as well as genetic and lifestyle factors. Treatment should be considered comprehensively and carried out under the guidance of doctors. Hypertension in children is closely related to neuroendocrine system. Hypertension in children may be related to dysfunction of the neuroendocrine system. The neuroendocrine system affects cardiovascular function and blood pressure regulation by regulating hormone secretion and action. The following are some possible mechanisms: 1. Renin-angiotensin-aldosterone system RAAS: RAAS plays an important role in the regulation of blood pressure. Angiotensinogen produces angiotensin I under the action of renin, angiotensin I produces angiotensin II under the action of angiotensin converting enzyme, angiotensin II can constrict blood vessels and increase aldosterone secretion, thus increasing blood pressure. In children with hypertension, RAAS activity may increase, leading to elevated blood pressure.2. Adrenaline and noradrenaline: Adrenaline and noradrenaline are neurotransmitters released by the sympathetic nervous system that act on adrenergic receptors on vascular smooth muscle cells, causing vasoconstriction and elevated blood pressure. In children with hypertension, sympathetic nervous system activity may increase, resulting in increased secretion of adrenaline and noradrenaline.3. Insulin: Insulin promotes sodium reabsorption by the kidneys, increasing blood volume and thus raising blood pressure.4. Other hormones: Insulin levels may increase in children with obesity or insulin resistance.5. Some other hormones, such as endothelin and vascular endothelial growth factor, may also be involved in the pathogenesis of childhood hypertension. In addition, childhood hypertension may also be related to genetic factors, diet habits, lifestyle, obesity and other factors. Some diseases, such as glomerulonephritis, adrenal diseases, etc., may also cause childhood hypertension. Therefore, for children with hypertension, it is necessary to consider the factors of neuroendocrine system, and carry out corresponding examination and treatment. Treatment methods include lifestyle changes, medication, etc. At the same time, blood pressure monitoring and related examinations are carried out regularly to evaluate the treatment effect and prevent complications. It should be noted that the diagnosis and treatment of hypertension in children need to be carried out under the guidance of a doctor. Parents should pay attention to their child's blood pressure and seek medical attention in time if there is any abnormality.