Diagnostic index of lupus erythematosus

Lupus Erythematosis diagnostic indicators mainly include clinical symptoms, blood test abnormalities, urine test abnormalities, pathological examination abnormalities, etc. 1. Clinical symptoms of patients may appear facial butterfly erythema, fever, fatigue, joint pain swelling, oral ulcers and other manifestations. Facial butterfly erythema is a more typical symptom, usually distributed in the bridge of the nose and bilateral zygomatic, symmetrical. Fever can be low fever or high fever, and often irregular fever. Fatigue may be more serious, affecting daily life. Joint symptoms can involve multiple joints, redness, pain, limited mobility, etc. Oral ulcer is also one of the common symptoms. 2. Blood test abnormalities include blood routine, erythrocyte sedimentation, autoantibody test, etc. Blood routine may show leukopenia, thrombocytopenia or anemia. Erythrocyte sedimentation rate (ESR) is usually accelerated. In autoantibody test, antinuclear antibody (ANA) can be abnormal in almost all patients, which is important for diagnosis. In addition, specific antibodies such as anti-double-stranded DNA antibody and anti-Sm antibody are also highly specific for the diagnosis of lupus erythematosus. 3. Abnormal urine test can find proteinuria, hematuria, etc., indicating kidney involvement. 4. Pathological examination abnormalities For some atypical cases, pathological examination such as skin biopsy is helpful to make a clear diagnosis. It should be noted that the diagnosis of lupus erythematosus requires comprehensive evaluation of various indicators and clinical manifestations. A single indicator abnormality may not be diagnosed. At the same time, it should be differentiated from other diseases with similar symptoms to ensure the accuracy of diagnosis. If lupus is suspected, seek medical attention promptly for a thorough examination and evaluation. The doctor will develop an individualized diagnosis plan based on the specific situation.