40-year-old menstruation does not come to do

40-year-old menstruation does not come, should seek medical attention in time for a comprehensive examination and evaluation to clarify the cause, and take appropriate measures. First, may be caused by endocrine disorders. 40-year-old women may be due to life stress, mood swings, bad habits and other factors leading to imbalance in hormone levels in the body, thus affecting the menstrual cycle. For example, long-term mental stress may interfere with the normal function of the hypothalamic-pituitary-ovarian axis, resulting in abnormal menstruation and even amenorrhea. Secondly, ovarian dysfunction is also one of the common causes. With age, ovarian function gradually declines, and there may be no ovulation or irregular ovulation, resulting in menstruation. Ovarian function can be assessed by tests such as sex hormone levels. Some diseases can also be caused. Polycystic ovary syndrome, which typically includes oligomenorrhea, amenorrhea, etc., may also be accompanied by hirsutism, acne, obesity, etc.; and thyroid dysfunction, whether hyperthyroidism or hypothyroidism, may affect menstruation. In addition, surgical injuries should not be ignored. If there has been a recent uterine surgery, it may cause damage to the endometrium, causing uterine adhesions and other problems, resulting in menstruation. Finally, long-term excessive diet, malnutrition and so on may also lead to menstruation. The body lacks essential nutrients to maintain normal physiological functions, including menstrual cycles.