Is cervical low-grade squamous intraepithelial lesion serious?

Low-grade cervical squamous intraepithelial lesions are not considered serious, but they should not be ignored.

Although low-grade cervical squamous intraepithelial lesions are at a lower risk of malignancy than high-grade cervical lesions, they still indicate abnormal changes in cervical cells. If they are not properly monitored and treated, there is still a possibility of progression.

Patients with low-grade cervical squamous intraepithelial lesions usually need close follow-up, including regular cervical cytology and HPV testing if necessary, to monitor whether the lesions persist, progress, or regress.

Some patients may resolve spontaneously, especially in young, immunocompetent people. However, some cases that persist or show signs of progression may require further treatment, such as local physical therapy.