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What causes the three plus signs of urine protein?


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3 + urinary protein, may be caused by interstitial nephritis, hypertensive nephropathy, a large number of muscle tissue damage and other reasons.
1, interstitial nephritis
interstitial nephritis can lead to renal tubular interstitial damage, so that its reabsorption capacity decreased, at this time glomerular normal filtration of small molecular protein can not be reabsorbed by renal tubules, causing renal tubular proteinuria, expressed as urinary protein 3+.
2, hypertensive nephropathy
hypertensive nephropathy patients with glomerular filtration membrane damage, resulting in protein filtration increased, more than renal tubular reabsorption capacity, resulting in glomerular proteinuria, urine routine examination will also show urinary protein 3+.
3, a large number of muscle tissue damage
muscle tissue contains a large number of hemoglobin, myoglobin, etc. When a large number of muscle tissue damage, can lead to blood free hemoglobin and myoglobin increased, can not be completely filtered and absorbed by the kidneys, resulting in proteinuria.