What is the treatment of smooth osteosarcoma?

Surgery combined with chemotherapy is the main treatment for smooth osteosarcoma, including surgery Osteosarcoma is a rare malignant tumor that occurs in children and adolescents. It is common in long bones of the limbs, especially the distal femur and proximal tibia. At present, surgery combined with chemotherapy is the main treatment for osteosarcoma. Surgical treatment: The aim of surgical treatment is to completely remove the tumor tissue, including normal tissue surrounding the tumor and possible metastatic lymph nodes. Surgical methods include tumor resection, amputation and limb salvage. For early smooth osteosarcoma, limb salvage can preserve limb function and improve the quality of life of patients. Chemotherapy: Chemotherapy is one of the important methods for smooth osteosarcoma treatment. Chemotherapy can kill tumor cells throughout the body, reducing the risk of recurrence and metastasis. Commonly used chemotherapy drugs include doxorubicin, cisplatin, ifosfamide, etc. Chemotherapy regimens are usually based on factors such as the patient's age, tumor size and location, and pathological type. Radiation: Radiation can be used to locally control tumors and reduce the risk of recurrence. Radiotherapy is usually performed after surgery and can also be used for the treatment of advanced or metastatic smooth osteosarcoma. Targeted therapy: In recent years, molecular targeted therapy for smooth osteosarcoma has also made some progress. Some targeted drugs such as imatinib and sunitinib can inhibit the growth and spread of tumor cells and improve the treatment effect. Rehabilitation therapy: After surgery, patients need rehabilitation therapy, including physical therapy, functional exercise, etc., to restore limb function and improve quality of life. It should be noted that the treatment of smooth osteosarcoma requires a comprehensive consideration of the patient's age, tumor size and location, pathological type, treatment response and other factors, to develop personalized treatment plan. In addition, patients and family members need to actively cooperate with doctors during treatment, pay attention to nutritional support and psychological adjustment, and improve treatment effect and quality of life.