What is the cause of pulmonary hypertension in children

The main causes of pulmonary hypertension in children include congenital heart disease, lung disease, left heart disease, respiratory system disease, genetic factors and other factors. Such as atrial septal defect, ventricular septal defect, patent ductus arteriosus, etc., can lead to increased left-to-right shunt, increased pulmonary artery blood flow, resulting in pulmonary hypertension. 2. Lung diseases: such as neonatal respiratory distress syndrome, pneumonia, atelectasis, etc., can lead to pulmonary vasoconstriction, increased pulmonary artery pressure. 3. Left heart disease: Such as cardiomyopathy, heart failure, etc., can lead to increased left atrial pressure, affect pulmonary artery through pulmonary vein, cause pulmonary hypertension. 4. Respiratory system diseases: such as plateau environment, chronic obstructive pulmonary disease, etc., can lead to hypoxemia and pulmonary vasoconstriction, causing pulmonary hypertension. 5. Genetic factors: Such as EIF2AK4, BMPR2 gene mutation, can lead to pulmonary artery smooth muscle cell proliferation and pulmonary vascular remodeling, causing pulmonary hypertension. 6. Other factors: such as drugs, poisons, autoimmune diseases, schistosomiasis, etc., can also cause pulmonary hypertension. It should be noted that the etiology of pulmonary hypertension is more complex, some causes may not be clear. For children with pulmonary hypertension, timely medical attention should be sought to clarify the cause and targeted treatment. At the same time, for high-risk groups, such as children with congenital heart disease, cardiac ultrasound should be performed regularly in order to detect and treat pulmonary hypertension early.