What is serological urticaria?

Serological urticaria is an allergic disease caused by the infusion of allogeneic serum or serum products, vaccines, etc.

When allogeneic serum enters the body, it stimulates the body to produce specific antibodies. When contacted again, it forms antigen-antibody complexes, causing mast cells to release inflammatory mediators, thus causing symptoms such as wheals. Common symptoms include rapid appearance of wheals of different sizes and shapes on the skin, often accompanied by itching. In severe cases, angioedema, dyspnea, abdominal pain

, etc.