Atypical squamous cells, meaning unknown, cancer?

Atypical squamous cells of unknown significance are generally not cancer.

Atypical squamous cells are an abnormal cell type observed on cytological examination, usually evaluated by smear staining and microscopic examination. The presence of cells may indicate an underlying pathological condition, but does not necessarily mean cancer. Atypical squamous cells can appear in a variety of circumstances, including inflammation, infection, injury, or other non-cancerous disease, and may also be signs of early cancer, such as precancerous lesions of cervical cancer.

If atypical squamous cells are found on smear examination, further examination is usually required to determine whether cancer or other pathological conditions exist.