Do you know about the genetic problems of thalassemia?

Thalassemia is divided into α-thalassemia and β-thalassemia. It is a hereditary hemolytic anemia disease, mainly caused by a defect in the globin gene, which reduces or fails to synthesize globin peptide chain. The patient's chromosome is missing an α-genome, which promotes the composition of hemoglobin to change, and then causes thalassemia.