Brain atrophy is generally characterized by

Normal brain atrophy is a change in brain morphology and structure discovered after brain CT or MRI examination. The main features are reduced brain tissue volume, brain parenchyma shrinkage, ventricular enlargement, and cerebral sulci widening. Clinically, there are brain atrophy, brainstem atrophy, and cerebellar atrophy, which can sometimes be combined to show different clinical symptoms. Brain atrophy often manifests as dementia and mental symptoms, such as frontal and temporal lobe atrophy, resulting in frontotemporal dementia. Striatum and substantia nigra atrophy of the brain stem, manifested as Parkinson's symptoms. Cerebellar atrophy manifested as ataxia, unstable movement, easy to fall when walking.