Is nodular prurigo serious?

Nodular prurigo is difficult to treat and itching is very severe, the itch of the general patient is difficult to stop and the rash is difficult to subside, in short, the patient feels very painful, but there are no special symptoms of the internal organs, although some patients show nodular prurigo but not this disease, but skin lymphoma or pemphigus or pemphigoid, then the patient's situation is more serious.