Can chickenpox get a second time?

Chickenpox doesn't get a second time, but the virus that causes it is called varicella-zoster virus. It can cause a second infection, and even third and fourth infections. But only the first of these infections is chickenpox. The rest of the second and subsequent infections are not called chickenpox, but herpes zoster. This is because the immune system does not recognize the virus at the time of the first infection, resulting in a systemic infection, with rashes appearing on the head, face, neck, trunk, and limbs. After this infection, the immune system maintains the relevant immune memory, so a second infection does not result in a systemic infection. A second infection results in a localized infection, with a localized rash called shingles. This is because after the first infection, the body's immune system recognizes the virus, and in the second infection, it is not a foreign virus that invades the body, but the virus after the first infection lurks in the nerve root cells, and when immunity is low, it reproduces and activates again to cause local infection. Local infection is limited to the area dominated by this nerve, and does not spread to other places.