Does Akebia have side effects on kidneys?

Akebia stem is easy to damage kidney function in large doses. In normal doses, it has basically no side effects. If the dose is too large or taken for too long, it is easy to damage kidney function, and even easy to show acute nephritis and uremia. It needs more attention. Therefore, it must be taken strictly according to the therapeutic dose. If the dose is too small, the therapeutic effect cannot be achieved. If the dose is too large, it is easy to show adverse reactions such as poisoning.