How does gastroesophageal reflux disease develop?

Gastroesophageal reflux disease is generally referred to as gastroesophageal reflux. The causes of gastroesophageal reflux usually include relaxation of the lower esophageal sphincter, defects in the esophageal wall, increased abdominal pressure, etc. Details are as follows:

1. Relaxation of the lower esophageal sphincter The

lower esophageal sphincter is a muscle ring connecting the esophagus and stomach. Under normal circumstances, it can be kept closed to prevent gastric contents from flowing back into the esophagus. If the sphincter relaxes, it will cause gastric acid and digestive fluids to flow back into the esophagus, causing gastroesophageal reflux.

2. Defects in the esophageal wall The

esophageal mucosa usually has a protective layer against acid stimulation. When the esophageal mucosa may be damaged or destroyed, it will be more sensitive to gastric acid and gastric juice. Even a small amount of gastric acid and digestive fluid enters the esophagus, which may cause gastroesophageal reflux.

3. Increased abdominal pressure

is also an important factor in the formation of gastroesophageal reflux. Increased intraabdominal pressure makes it easy for gastric acid to flow into the esophagus, thus causing gastroesophageal reflux.