Treatment of Pulmonary Hemorrhagic Nephritis Syndrome

According to the management of PHNS, the following is a serious medical summary: 1. Diagnosis Clinical manifestations: PHNS mainly presents with hemoptysis, anemia, dyspnea and rapid progressive glomerulonephritis. Laboratory tests: anti-glomerular basement membrane antibody positive, complement decreased, renal dysfunction. Kidney biopsy: helpful to determine the diagnosis and extent of the disease. 2. Intensive immunosuppressive therapy: glucocorticoid combined with cytotoxic drugs such as cyclophosphamide is preferred. Plasma exchange: anti-glomerular basement membrane antibodies are cleared. Symptomatic and supportive treatment: anemia, water electrolyte disorder, blood pressure control, infection prevention. 3. Complications: acute kidney injury: dialysis treatment. Infection: active anti-infection treatment. Pulmonary hemorrhage: Hemostatic treatment, such as the use of hemostatic drugs, blood transfusion, etc. 4. Poor prognosis, high mortality. Early diagnosis and treatment is very important for prognosis. 5. Children in special populations: treatment similar to adults, but pay attention to drug dosage and side effects. Elderly patients: physical function decline, increased risk of complications, treatment needs to be individualized. 6. Follow-up regular review of renal function, anti-glomerular basement membrane antibody and other indicators. Monitor the disease changes, timely adjust the treatment plan. The above content is for reference only, the specific treatment plan should be formulated according to the specific conditions of the patient, it is recommended to treat under the guidance of professional doctors.