Endometriosis What is Endometriosis

Endometriosis can be treated with nonsteroidal anti-inflammatory drugs, progestins, contraceptives, gonadotropin-releasing hormone agonists, etc., but it is usually difficult to completely cure by drugs alone. 1. Nonsteroidal anti-inflammatory drugs, such as ibuprofen, are mainly used to relieve the pain caused by endometriosis. Prostaglandins reduce pain by inhibiting prostaglandin synthase activity. However, they do not fundamentally solve the problem of endometriosis. 2. Progestins can cause decidual-like changes in the endometrium, eventually leading to endometrial atrophy. However, long-term use may bring some side effects, such as weight gain, breakthrough bleeding, etc. 3. Contraceptives Contraceptives can inhibit ovulation, reduce estrogen levels in the body, and make the endometrium atrophy and degenerate. It is more suitable for patients with contraceptive needs and mild conditions, but the effect may be limited for those with severe conditions. 4. Gonadotropin-releasing hormone agonists Gonadotropin-releasing hormone agonists can strongly inhibit ovarian function, causing low estrogen status in the body, causing ectopic endometrium to atrophy. However, it may cause climacteric symptoms, such as hot flashes, night sweats, etc., and it is easy to relapse after discontinuation. It should be noted that the effect of drug treatment varies from person to person, and each drug has its limitations and side effects, so drugs must be used according to medical advice.