How does spondylitis come about?

The causes of spondylitis are complex, mainly including genetic factors, infection factors, autoimmune factors, environmental factors, endocrine factors, etc. 1, genetic factors If there are spondylitis patients in the family, the risk of their relatives is relatively high. Abnormality of some genes may lead to imbalance of immune tolerance of the body to autoantigens, thus triggering an immune response to attack the spine and other parts. 2. Infection factors After infection by pathogens such as bacteria and viruses, the immune system of the body may induce the immune response against its own tissues through molecular simulation, which may lead to the occurrence of spondylitis. 3. Autoimmune factors The immune system of the body mistakenly regards spinal joints as foreign bodies for attack, resulting in continuous occurrence and persistence of inflammatory reactions, gradually destroying the structure and function of the spine. 4, environmental factors long-term in a cold, humid environment, may affect the blood circulation around the spine, reduce the resistance of the spine, increase the possibility of spondylitis. 5, endocrine factors Changes in hormone levels in the body may affect the balance of the immune system, thus promoting or inducing the emergence of spondylitis to a certain extent. In short, the occurrence of spondylitis is the result of the interaction of many factors, and it is important to understand the above factors for the diagnosis, treatment and prevention of spondylitis.