What are the genetic characteristics of familial adenomatous polyposis?

The genetic characteristics of familial adenomatous polyposis are autosomal dominant genetic disease and the incidence of offspring is high.

Familial adenomatous polyposis is mainly caused by genetic variation, 75%-80% of patients are due to genetic disease. 20%-25% are non-genetic, new patients with genetic mutation. The offspring of patients with variant APC gene will continue dominant inheritance. Patients are generally asymptomatic in the early stage, and most of them are detected during physical examination.

This disease has a high risk of malignant transformation. After diagnosis, patients should remove the lesions as soon as possible through surgery and develop good eating habits daily.