Side effects of paclitaxel carboplatin chemotherapy

The side effects of paclitaxel carboplatin chemotherapy mainly include gastrointestinal reactions, allergic reactions, bone marrow suppression, neurotoxicity, liver and kidney function damage, etc. 1. Gastrointestinal reactions are often manifested as nausea, vomiting, loss of appetite, etc. Severe nausea and vomiting will affect the patient's food and nutrition intake, and reduce the quality of life. 2. Allergic reaction Paclitaxel may cause allergic reaction, such as rash, itching, dyspnea, etc., severe anaphylactic shock may occur, usually need pretreatment before medication to prevent allergic reaction. 3. Bone marrow suppression Paclitaxel and carboplatin may cause bone marrow hematopoietic function inhibition, causing leukopenia, thrombocytopenia and anemia. Leukopenia can reduce immunity and increase the risk of infection; thrombocytopenia can lead to bleeding tendencies, such as skin petechiae, ecchymosis, epistaxis, etc.; anemia can cause fatigue, dizziness and other symptoms. 4. Neurotoxicity is mainly manifested as peripheral neuropathy such as numbness of hands and feet, paresthesia, muscle pain, etc., which may affect the daily life and activity ability of patients. 5. Liver and kidney function damage can lead to elevated liver enzymes, elevated bilirubin, and abnormal renal function. Regular monitoring of liver and kidney function is required to detect and deal with abnormal conditions in time. Medical staff need to pay close attention to the side effects of chemotherapy, timely give corresponding treatment and support treatment, so as to alleviate the pain of patients and ensure the smooth progress of chemotherapy. At the same time, patients and family members should also understand these side effects, actively cooperate with treatment and nursing, and inform medical staff in time if there is discomfort.