malignant peripheral nerve sheath tumor

Malignant peripheral nerve sheath tumors are rare but aggressive tumors.

Malignant peripheral nerve sheath tumors originate from cells in the peripheral nerve sheath and usually exhibit rapid growth and infiltration of surrounding tissue. These tumors may occur anywhere in the body, but are common in the extremities, trunk, and head and neck. Patients may experience localized pain, lumps, and neurological disorders such as paresthesia, limited movement, etc. The severity of symptoms depends on the location and size of the tumor.

Because it is relatively rare and symptoms may be atypical, diagnosis of malignant peripheral nerve sheath tumors can be challenging. Treatment usually requires a combination of surgical resection, radiation, and chemotherapy. The goal of surgery is to remove the tumor as completely as possible, but complete removal is sometimes difficult due to the aggressive nature of the tumor. Radiotherapy and chemotherapy can be used as adjuvant therapy to reduce the risk of recurrence and control tumor progression.

Despite aggressive treatment, the prognosis of malignant peripheral nerve sheath tumor remains unsatisfactory. Recurrence rates are high and distant metastases, especially to organs such as the lungs

, are prone to occur

.