4 radiation-insensitive tumors

1. Osteosarcoma is not sensitive to radiotherapy, mainly because of the characteristics of tumor cells themselves. 2. Radiotherapy-resistance of melanoma may be related to its high heterogeneity and specific gene changes. 4. Clear cell carcinoma of kidney The poor effect of radiotherapy on clear cell carcinoma of kidney may be due to its rich blood supply and complex tumor microenvironment, which makes it difficult for radiotherapy to fully exert its effect. In clinical practice, for these radiation-insensitive tumors, it is necessary to comprehensively consider other treatment methods, such as surgery, chemotherapy, targeted therapy, etc., to develop more appropriate individualized treatment protocols to improve the survival rate and quality of life of patients. At the same time, it is also necessary to continuously study the characteristics and mechanisms of these tumors and explore new treatment strategies to improve the treatment effect.