Causes and harm of high total bilirubin

High total bilirubin can be divided into direct bilirubin elevation and indirect bilirubin elevation for different reasons.

1. Direct bilirubin elevation

gallstones, biliary tract tumors, etc. can lead to biliary obstruction, so that bile cannot be discharged normally, and reflux into the blood, resulting in direct bilirubin elevation.

2. Indirect bilirubin elevation The

bilirubin in the body is mainly derived from red blood cells. When the patient has chronic hepatitis, acute hepatitis, alcoholic hepatitis and other diseases, it may cause certain damage to the liver, resulting in an impact on cell metabolism, thus affecting the production of indirect bilirubin, resulting in an increase in indirect bilirubin.

The hazards of high total bilirubin include hepatocellular jaundice, obstructive jaundice, hemolytic jaundice, etc.

1, hepatocellular jaundice elevated

total bilirubin represents liver function has been damaged, may affect the excretion of bilirubin, causing hepatocellular jaundice.

2. Obstructive jaundice

total bilirubin is related to biliary obstruction, which can lead to incomplete excretion of bile from the body, causing obstructive jaundice.

3. Hemolytic jaundice Elevated

bilirubin can affect coagulation function, leading to coagulation dysfunction, causing hemolytic jaundice.