Causes of duodenal perforation

The main causes of duodenal perforation include Helicobacter pylori infection, trauma or surgery, and drug stimulation.

1. Helicobacter pylori infection

can lead to duodenal mucosal damage, and in severe cases it is easy to cause perforation, resulting in duodenal perforation.

2. Trauma or surgery

All kinds of violence or upper abdominal surgery, resulting in severe duodenal damage, resulting in duodenal perforation.

3. Drug stimulation

If the patient takes non-steroidal anti-inflammatory drugs for a long time, it is easy to cause severe gastrointestinal mucosal damage, resulting in perforation of ulcers, such as ibuprofen, meloxicam, acetaminophen, etc.