How is gastrointestinal polyps caused?

Gastrointestinal polyps refer to intestinal polyps and gastric polyps. Intestinal polyps are related to chronic inflammation stimulation and genetic factors; gastric polyps are related to Helicobacter pylori infection, long-term use of proton pump inhibitors and bile reflux. 1. Causes of intestinal polyps 1. Chronic inflammation stimulates intestinal mucosa. Long-term chronic inflammation may lead to intestinal mucosa damage, causing local intestinal mucosa epithelium or cell proliferation, and eventually forming intestinal polyps. 2. Genetic clinical findings. When someone in the family has intestinal polyps, the probability of other family members suffering from the disease will be significantly increased. Therefore, it is believed that the disease has certain familial heredity. II. Causes of gastric polyps 1. Helicobacter pylori infection Helicobacter pylori infection is a common cause of chronic gastritis. After chronic gastritis, gastric mucosa will be repeatedly stimulated by inflammation, which will easily lead to regeneration of gastric epithelial cells, thus forming gastric polyps. 2. Long-term application of proton pump inhibitors Long-term application of proton pump inhibitors such as omeprazole, lansoprazole and pantoprazole may cause the human body to be in a state of low gastric acid, which is also easy to increase the risk of stomach polyps. 3. Bile reflux Bile reflux into the stomach is easy to induce inflammatory reaction in gastric mucosa. When a large amount of bile flows back into the stomach, it may destroy the acidic environment in the stomach and finally form gastric polyps.