How is hyponatremia caused by hepatorenal syndrome

Hepatorenal syndrome dilution hyponatremia is considered to be caused by liver failure, renal function damage, water and sodium retention, etc.

1. Liver failure Under

normal circumstances, the liver plays an important role in balancing water and maintaining osmotic pressure in the process of synthesizing and decomposing substances. When suffering from hepatorenal syndrome, the liver can not normally synthesize proteins and other substances, the ability to regulate plasma osmotic pressure decreases, so dilution hyponatremia can occur.

2, renal function damage

hepatorenal syndrome will lead to decreased renal blood perfusion, thus affecting the filtration function of the kidneys. In addition, the metabolism of antidiuretic hormone in the liver is also affected, resulting in reduced secretion of antidiuretic hormone, further exacerbating poor urinary excretion and water-salt balance, and ultimately inducing dilutive hyponatremia.

3, water and sodium retention

due to liver and kidney function damage, can not effectively discharge excess water and sodium ions in the body, will lead to water and sodium retention in the body, but because the blood sodium is diluted, and then cause dilution hyponatremia.