What is quadruple therapy to eradicate Helicobacter pylori?

The quadruple therapy for eradication of Helicobacter pylori refers to the treatment of four drugs at the same time, including a proton pump inhibitor, a bismuth agent and two antibiotics.

1. Proton pump inhibitor

Proton pump inhibitor can inhibit gastric acid secretion and create conditions for antibiotics sterilization. Commonly used drugs include rabeprazole, omeprazole, pantoprazole, etc.

2. Bismuth agent

Bismuth agent can protect gastric mucosa, promote gastric mucosa repair, and help inhibit Helicobacter pylori.

3. Antibiotics

Antibiotics are key drugs for the treatment of Helicobacter pylori infection. Combined with the above drugs can eliminate Helicobacter pylori. Antibiotics such as clarithromycin, amoxicillin, metronidazole, levofloxacin, etc. are generally selected.