How is internal rheumatism caused?

Rheumatoid disease is closely related to many factors, including genetic factors, infection factors, etc. Genetic factors cause susceptibility to rheumatoid arthritis, infection may trigger the disease, and many complex pathogenic factors participate in the pathogenesis of rheumatoid arthritis. Family investigation and twin prevalence studies suggest that genetic factors determine susceptibility to rheumatoid arthritis, but family aggregation of rheumatoid disease is relatively low. Among the genetic factors, the most important is the antigen of human white blood cells, which is closely related to the incidence of rheumatoid arthritis. If there is a background of this gene, in the case of co-infection, it may trigger the onset of rheumatoid arthritis, which is the cause of rheumatoid arthritis.