What about tophite?


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The appearance of tophite marks the beginning of chronic gouty arthritis. Small tophite in the early stage can disappear with timely application of medical treatment. Tophite is mainly due to urate crystallization and fusion, so tophite disappearance is mainly due to the application of anti-uric acid drugs. As long as the blood uric acid level is controlled below 300μmol/L, the urate crystals can gradually dissolve and tophite will gradually disappear. However, for some particularly large tophones, chronic filament entanglement has been formed, and the application of anti-uric acid drugs may not be good, requiring surgical resection. If tophones exist for a long time, they will cause bone destruction, affect joint function, and sometimes cause local skin ulceration and infection, affecting the patient's quality of life. once tophones are shown, drug treatment must be applied in time.