What are the diagnostic criteria for hepatolenticular degeneration?

The diagnosis criteria of hepatolenticular degeneration include gene detection, liver copper content, slit lamp examination and other methods. The specific analysis is as follows:

1. Gene detection

Because hepatolenticular degeneration belongs to autosomal recessive genetic disease, if the patient has no obvious clinical symptoms, it can be confirmed whether he has hepatolenticular degeneration through gene detection.

2. Liver copper content is

determined by detecting liver copper content in the body. If the examination result is higher than 250μg/g dry weight, and acute and chronic liver diseases with unknown causes occur, the diagnosis can be made.

3. Slit lamp examination

is performed through ophthalmic slit lamp examination. If K-F ring appears, that is, brown green ring of corneal limbus, hepatolenticular degeneration can be diagnosed.