What causes nonalcoholic fatty liver disease?

Nonalcoholic fatty liver disease may be related to genetic susceptibility, overnutrition, drug side effects and other factors.

1. Genetic susceptibility

Nonalcoholic fatty liver disease has a certain relationship with heredity. When one or both parents suffer from nonalcoholic fatty liver disease, the probability of their offspring suffering from nonalcoholic fatty liver disease will be relatively increased.

2. Overnutrition

is caused by overeating or eating too much food with high fat, high calories, high cholesterol and high sugar, resulting in excessive fat accumulation in liver cells, affecting normal liver function.

3. Drug side effects such

as methotrexate, tamoxifen and glucocorticoids can cause damage to liver cells, inhibit lipoprotein synthesis and hinder liver fat metabolism, thus causing nonalcoholic fatty liver disease.