What are the causes of homocysteine?


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High homocysteine may be related to non-pathological factors, but also may be related to lupus nephritis, coronary heart disease and other pathological factors.
First, non-pathological factors such
as insufficient intake of B vitamins, excessive intake of methionine, smoking and alcohol, etc., may increase homocysteine production or metabolism, resulting in high homocysteine.
Second, pathological factors
1. Lupus nephritis
Lupus nephritis is caused by the accumulation of immune complexes in the glomerulus inflammatory kidney damage, can hinder homocysteine metabolism, so that its level increases.
2. Coronary
heart disease is due to coronary artery stenosis, obstruction caused by heart disease, can lead to homocysteine metabolic enzyme activity decreased, causing homocysteine increased.