Can cartilage regenerate

Cartilage cannot regenerate due to lack of blood vessels and nerve innervation, but some methods can be used to promote cartilage tissue regeneration. For example, for localized small cartilage defects, bone marrow can flow out through drilling or microfracture to fill the surface of cartilage damage. After appropriate rehabilitation training, bone marrow mesenchymal stem cells can be differentiated into fibrocartilage similar to hyaline cartilage to fill the cartilage defect. However, the regenerated tissue cannot be completely hyaline cartilage, but only fibrocartilage close to hyaline cartilage, but it is better than the defect itself, so theoretically, cartilage damage cannot be regenerated.