HPV16 positive should be tested.

HPV16 does not necessarily need to be biopsied, or according to the specific situation to analyze. At this stage, HPV infection in China women is still very common, HPV infection is divided into high-risk and low-risk two subtypes. There are 14 high-risk subtypes, China most common is 16, 18, 52, 58, but infected HPV does not necessarily mean cervical cancer. HPV is human papilloma virus, virus infection can cause cervical lesions, lesions may become cancer, but more often HPV infection only causes inflammatory changes, this time does not need special treatment, only need anti-viral infection treatment can, so HPV16 positive also combined with other examination results, gynecologists colposcopy to observe tissue mucosa, cervical mucosa has no problems. If the overall mucosa is smooth and there is no erosion, bleeding, necrosis, etc., only TCT, i.e. cervical cytology, may be needed for screening. If TCT is negative and HPV16 is only positive, cervical biopsy may not be needed, but follow-up observation after treatment is needed. However, if HPV16 is positive, cervical TCT results are also problematic. For example, when showing low-grade or high-grade lesions, cervical biopsy is required, so HPV16 positive should also be combined with other conditions to see whether to do biopsy.