What is the harm of long-term insomnia?

Long-term insomnia is easy to cause dizziness, headache, listlessness, loss of appetite and other discomfort symptoms, but also lead to endocrine disorders, causing acne, obesity, rough skin, etc.; long-term insomnia can also lead to decreased immunity, easy to induce colds and other diseases, insomnia on memory, attention, mood and other aspects will also produce harm.